The Role of Folic Acid, Vitamin B6, and Vitamin B12 in Cardiovascular Health

The Role of Folic Acid, Vitamin B6, and Vitamin B12 in Cardiovascular Health

This Georgetown Dialogue convened leading researchers to review the scientific evidence on the relationship between folic acid, vitamin B6, vitamin B12, homocysteine, and heart health. The roundtable discussion concluded with a lively discussion about whether there is sufficient strength of evidence to warrant communicating important information about this relationship to health professionals and consumers.

The deliberations of the experts on the claim that could be made on food labels is captured in this publication. Sixty-seven references are listed. Edited by M. Storey. Please contact us at cfnap@umd.edu to obtain a copy of the conference proceedings.

TABLE OF CONTENTS (in part)

Executive Summary

Scientific Review

Background and Regulatory Considerations of Fortification
Beth Olson, Ph.D.

Intakes and Food Sources among Target Populations
Katherine Tucker, Ph.D.

Epidemiology of Folate, Vitamins B6 and B12 in Heart Disease
Eric Rimm, Ph.D.

Review of Folate and Vitamin B12 Studies
Jacob Selhub, Ph.D.

Review of Vitamin B6 Studies
Killian Robinson, M.D.

Genetics and Potential Mechanisms of Action
Simonetta Friso, Ph.D.

Research Status and Future Direction
John Scott, Ph.D.